A study done by a Massachusetts General Hospital found that teens with bipolar disorder are at a greater risk of smoking and substance abuse. "This work confirms that bipolar disorder in adolescents is a huge risk factor for smoking and substance abuse, as big a risk factor as juvenile delinquency," study leader Dr. Timothy Wilens, director of substance abuse services in MGH Pediatric Psychopharmacology, said. He added "It could be that the onset of mood dysregulation in adolescence puts kids at even higher risk for poor judgment and self-medication of their symptoms," Wilens said. "It also could be that some genetic switch activated in adolescence turns on both BPD and substance abuse in these youngsters. That's something that we are currently investigating in genetic and neuro-imaging studies of this group." Someone in my family has BPD and it was found when she was a teen and she smokes to this day. I wonder if she has what they found in this study.